Mutations in Theileria Annulata Cytochrome B Gene Associated with Buparvaquone Resistance in Cattle, Egypt

Sequence Polymorphism of Cytochrome b Gene in Theileria annulata Tunisian Isolates and Its Association with Buparvaquone Treatment Failure

BACKGROUND Buparvaquone (BW 720C) is the major hydroxynaphtoquinone active against tropical theileriosis (Theileria annulata infection). Previous studies showed that buparvaquone, similarly to others hydroxynaphtoquinone, probably acts by binding to cytochrome b (cyt b) inhibiting the electron transport chain in the parasite. Several observations suggested that T. annulata is becoming resistant...

Chemotherapeutic Value of Parvaquone and Buparvaquone Against Theileria annulata Infection in Cattle

CLINICAL, DIAGNOSTIC AND THERAPEUTIC STUDIES ON THEILERIASIS (Theileria annulata) IN CATTLE IN UPPER EGYPT

The goal of the present study is to evaluate the endemic situation of theileriasis in the different localities in Upper Egypt, and also to evaluate the efficacy of some drugs in treatment of acute and chronic theileriasis. A total of 120 cows showed clinical signs varied from rise of body temperature, nasal and ocular discharge, corneal opacity, diarrhea, pale mucous membranes, associated with ...

Biochemical, Hematological studies in cattle naturally infected with Theileria annulata

The aim of the present study dealt with biochemical and hematological changes in cattle which presented to the Azad clinic of veterinary school in Urmia during the period between Dec 2008 to January 2012. A total of 985 cattle with positive theileriosis were examined. Data were collected on hematological conditions of the cattle. Ages of these slaughtered buffaloes ranged from 6 to 9 years, (79...

Complement-fixing antibodies in cattle experimentally infected with Theileria annulata or vaccinated with tissue cultures